Can We “Hack” Our Way to Some New Solutions for Lyme?

Reflections from a Promising Dialogue at the AAAS Conference in Washington, DC, November 17-18

by Lia Gaertner, BAL Science Committee

AAAS_Logo and magSome weeks ago, two members of the Bay Area Lyme Foundation Science Committee, Wendy Adams and Lia Gaertner, attended a leadership symposium in Washington, DC, sponsored by the American Association for the Advancement of Science (AAAS) and entitled, “Innovations-X: Rising Above the Politics for Progress in Science.”  The AAAS is the world’s largest general scientific society, with more than 125,000 individual and institutional members, and the publisher of Science magazine. Its mission is “to advance science, engineering, and innovation throughout the world for the benefit of all people.” At this event, there were three “wicked problems” discussed over two days: climate change, global/mobile health, and Lyme disease.  This blog, written by Lia Gaertner, will focus only on the Lyme portion of the conference.

The Steven & Alexandra Cohen Foundation Grants $6.5 Million to Bay Area Lyme Foundation

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Media Contact:
Tara DiMilia, 908-947-0500, tara.dimilia@TMstrat.com

The Steven & Alexandra Cohen Foundation Grants $6.5 Million to
Bay Area Lyme Foundation

Gift is part of the largest private donation for Lyme disease research—100% of grant will go directly to Lyme disease research programs.

SILICON VALLEY, California, December 17, 2015 –The Bay Area Lyme Foundation today announced that it received a $6.5 million grant from the Steven & Alexandra Cohen Foundation, the largest private donation ever given to Lyme disease research. The gift will support Bay Area Lyme’s mission of using new scientific research and innovations to make Lyme disease easy to diagnose and simple to cure.

“I was shocked to learn how many people suffer from Lyme disease in silence, and how much we still need to do to raise awareness and help find a cure,” said Alex Cohen, President of the Steven & Alexandra Cohen Foundation. “This gift is incredibly personal to me as I have experienced, first-hand, the chronic and debilitating side effects of this relatively unknown disease. We share Bay Area Lyme Foundation’s desire to find a cure for Lyme disease and hope that this gift will help pave the way to that important work.”

Bay Area Lyme Foundation Announces Grant Application for Two $100,000 Awards for Lyme Disease Research

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Media Contact:
Tara DiMilia, 908-947-0500, tara.dimilia@TMstrat.com

Bay Area Lyme Foundation Announces Grant Application for Two $100,000 Awards for Lyme Disease Research

‘Emerging Leader Award’ aims to attract new scientific talent to address scientific challenges of Lyme disease

Silicon Valley, California, October 5, 2015—The Bay Area Lyme Foundation, a leading national funder of Lyme disease research in the US, today announced a call for applications for two $100,000 Bay Area Lyme Foundation ‘Emerging Leader Award’ grants.  These awards will be given to two promising scientists who embody the future of leadership in Lyme disease research in the US.  The award recipients will be researchers in academia or the private sector who are currently at the post-doctoral level through the assistant Professor level, or equivalent, who have identified a defined approach to improve diagnostics or therapies for Lyme disease. Important criteria include demonstrated professional and scientific leadership in the biomedical sciences and a strong supporting scientific rationale for the project.  Research efforts funded by the award are required to generate initial proof of concept within 12–18 months.

Investigating and Living with the Elusive Culprit of Lyme Disease

Why is it that Lyme disease is so little understood, so hard to diagnose, and so frustratingly difficult to get treated? Such were the questions discussed last night at the first of the new Bay Area Lyme Foundation Speaker Series talks.

Field Mustard by Robert Buelteman
Field Mustard by Robert Buelteman

2014 Emerging Leader AwardJerome Bouquet recipient Jerome Bouquet, PhD, UCSF, began the program with a compelling overview of the history of Lyme disease and its pathology, highlighting some of the complicated attributes of the Lyme-causing spirochete and the manifestations of its infection. He touched on promising new technologies like the Tick Chip and the IBIS-developed Iridica, which use unbiased DNA amplification and multiplex assays with greater sensitivity (and more immediate results) than traditional methods. He also described promising developments in transcriptomics that have illustrated the lingering effects of the disease up to six months after treatment, and

New Study Reveals Ticks in Bay Area Carry Larger Diversity of Bacteria Than Expected and May Help Explain Why Lyme Disease Symptoms Vary Widely Among Bay Area Patients

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Tara DiMilia, 908-947-0500, tara.dimilia@TMstrat.com

New Study Reveals Ticks in Bay Area Carry Larger Diversity of Bacteria Than Expected and May Help Explain Why Lyme Disease Symptoms Vary Widely Among Bay Area Patients

Rates of tick infection with Borrelia miyamotoi are found to be higher in the Bay Area than previously documented on East Coast, and Tick-borne disease infection risk is shown to be higher in Redwood habitats than previously believed

SILICON VALLEY, Calif., August 19, 2015 — Bay Area Lyme Foundation, which is working to make Lyme disease easy to diagnose and simple to cure, highlights a new Bay Area study  conducted by researchers from Stanford and Northern Arizona Universities documenting a vast diversity of bacterial species and strains that cause tick-borne diseases in Bay Area residents and visitors.  The variety of bacterial species and strains identified may be the reason that Bay Area patients with tick-borne diseases experience a wide range of symptoms, which may or may not include flu-like complaints, joint pain, fatigue and a rash of differing shapes, thereby making exact diagnoses extremely difficult.

Bay Area Lyme Foundation Awards Grant to Harvard Medical School Researchers for Development of an Accurate Test for Lyme Disease

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Tara DiMilia, 908-947-0500, tara.dimilia@TMstrat.com

Bay Area Lyme Foundation Awards Grant to Harvard Medical School Researchers for Development of an Accurate Test for Lyme Disease

2015 Emerging Leader Award Seeks to Accelerate Scientific Solutions for Lyme Disease

PORTOLA VALLEY, CA — Bay Area Lyme Foundation, the leading national nonprofit funder of innovative Lyme disease research, today announced that the winners of its 2015 Emerging Leader Award, are collaborators Nira Pollock, MD, PhD, and John Branda, MD. The $100,000 grant that accompanies this award will support their research on a potential biomarker for Lyme disease, which may lead to the development of a novel urine test for early Lyme disease. The most commonly used diagnostic for Lyme disease, the two-tier serological ELISA/Western Blot process, misses up to 60% of cases of early stage Lyme.

LymeAid Brings Celebrities and Scientists Together To Accelerate Medical Breakthroughs for Lyme Disease

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Media Contact:
Tara DiMilia, 908-947-0500, tara.dimilia@TMstrat.com

Bay Area Lyme Foundation’s LymeAid Brings Celebrities and Scientists Together to Help Accelerate Medical Breakthroughs for Lyme Disease

David and Yolanda Foster, Daryl Hall, Huey Lewis, Jane Seymour, and Elet Hall were among supporters to help combat the fastest growing vector-borne infectious disease

PORTOLA VALLEY, CA — On Sunday, May 17, Bay Area Lyme Foundation, the leading national nonprofit funder of innovative Lyme disease research, hosted more than 400 celebrities, philanthropists, and noteworthy scientists at the third annual LymeAid® gala. The benefit dinner and concert raised approximately $600,000, of which 100% will go directly to fund research for Lyme disease.  More than 300,000 Americans are diagnosed with this potentially debilitating disease each year. 

Interview with ELA Recipient Lisa Blum

Lisa Blum is an enterprising young scientist and postdoctoral fellow at Stanford University School of Medicine, working in the lab of Dr. Bill Robinson. Earlier this year she was recognized as a Bay Area Lyme Foundation Emerging Leader and received a $100,000 project grant. Here she talks about her research, life at Stanford, and the impact of the award.  

2014 Blum ELA picture Resized_156

Q: Earlier this year, your project, “Sequencing of Antibody Responses to Borrelia burgdorferi Infection — Generation of Recombinant Antibodies with Diagnostic and Therapeutic Utility” helped earn you recognition as a Bay Area Lyme Emerging Leader.  Tell us about your project and what you hope to accomplish.

Antibodies are proteins produced by the immune system that protect us from infections, but in some cases the antibodies themselves can damage the human body. Our goal is to characterize antibodies produced during different stages of Lyme disease, and to generate monoclonal antibodies that can be used to improve on existing Lyme disease treatments and diagnosis.