Dr. Somer DelSignore: Congenital Lyme, PANS/PANDAS & Hope for Families

Ticktective Podcasts

Somer Delsignore, DNP

Dr. Somer Delsignore, DNP, is a Doctor of Nursing Practice and board-certified pediatric nurse practitioner specializing in complex chronic illness in children. Her clinical work focuses on the diagnosis and management of immune dysfunction using a root-cause approach. She developed the R.E.S.E.T. Protocol using a Root Cause lens to treat Immune Dysfunction systematically. A fellow of MAPS and AAOT and a member of ILADS, her expertise includes autoimmune, neuroimmune, and psychiatric manifestations of infectious diseases, especially tick-borne illnesses, as well as links to Autism Spectrum Disorder, PANS/PANDAS, and autoimmune encephalopathy. Delsignore completed her graduate and doctoral training at the University of Pennsylvania and SUNY Upstate Medical University, graduating magna and summa cum laude, and trained at leading pediatric centers, including Children’s Hospital of Philadelphia (CHOP), Penn State Children’s, and Children’s Health in Dallas. She is the CEO and Founder of Hudson Valley Integrative Health in Beacon, New York.

Bay Area Lyme Foundation Highlights Research Leadership and Momentum in Tick-Borne Disease, Names New Executive Director

FOR IMMEDIATE RELEASE

 

Bay Area Lyme Foundation Highlights Research Leadership and Momentum in Tick-Borne Disease, Names New Executive Director

Milestones include FDA-cleared diagnostics enabled by Lyme Disease Biobank, the launch of Bay Area Lyme Ventures, and 10 years since Lyme Disease Biobank provided its first samples, advancing the field

PORTOLA VALLEY, Calif., February 11, 2026Bay Area Lyme Foundation, a national nonprofit and leading sponsor of tick-borne disease research, today reflected on concrete progress in 2025 that demonstrates the maturation of more than a decade of investment in diagnostics, therapeutics, and research infrastructure for Lyme and other tick-borne diseases. As Bay Area Lyme Foundation-supported programs advance towards being available for clinicians and patients, the organization announced David A. Walsey, JD, LLM, as Executive Director. He has extensive experience offering strategic guidance to life sciences companies and a personal connection to Lyme disease that will help guide the foundation’s next phase of scientific translation and organizational growth.

In 2025, Bay Area Lyme Foundation reached an important inflection point as new diagnostic tests enabled by the foundation’s Lyme Disease Biobank secured FDA clearance. These new tests highlight the potential to move from discovery-stage research toward tools that can meaningfully improve patient care. The organization also launched Bay Area Lyme Ventures, an investment arm designed to help promising diagnostics and therapeutics move more efficiently from the laboratory into real-world use, while also creating the opportunity for returns to support future Bay Area Lyme Foundation research. This progress underscores the importance of the more than $30 million in research Bay Area Lyme Foundation has invested at leading academic and medical institutions such as Stanford, Johns Hopkins, Tulane, and Duke. Research supported by the foundation has produced over 70 peer-reviewed scientific publications and sustained collaboration across top research centers nationwide.

Meet David Walsey: Our New Executive Director

Ticktective Podcasts

David A. Walsey, JD, LLM

David Walsey joined Bay Area Lyme Foundation as Executive Director in 2025. He is a strategic biotech leader with 25 years of experience advancing corporate objectives through strategy, communications, financing, and investor initiatives for public companies. Most recently, David served as Senior Vice President, Corporate Affairs at MEI Pharma, leading programs spanning corporate strategy, investor relations, and corporate communications. He previously held senior roles at Alder Biopharmaceuticals, Optimer Pharmaceuticals, Sarepta Therapeutics (formerly AVI BioPharma), Arena Pharmaceuticals, and Maxim Pharmaceuticals, and worked at agencies including Real Chemistry (formerly W20 Group), The Ruth Group, and Noonan Russo. He began his career as an attorney in private practice in New York City and holds an LL.M. in Taxation from New York University School of Law, a J.D. from Brooklyn Law School, and a B.A. from Franklin and Marshall College.

Amy Offutt, MD: Lyme, Integrative Medicine, & True Healing

Amy Offutt, MD

Amy Offutt, MD

Dr. Offutt is the medical director and co-owner of Heart & Soul Integrative Health and Yoga which she co-founded with her husband, Brad, in 2007, located in Marble Falls, Texas. Her first seven years of practice were focused on rural family medicine and obstetrics after which she transitioned to approach the treatment of chronic inflammatory diseases using integrative medicine. She completed medical school at The University of Texas Health Sciences Center in San Antonio and completed a residency in Family Medicine at Christus Health. She has completed a fellowship with the American Academy of Anti-Aging and Regenerative Medicine and has a Master’s Degree in Integrative Medicine from George Washington University.

Dr. Casey Kelley: From Lyme & Mold to Optimum Health

Dr Casey Kelley

Bay Area Lyme Spotlight Series

 

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In a powerful Ticktective™ episode, host Dana Parish sits down with Casey Kelley, MD, Founder and Medical Director of Case Integrative Health, to unpack the complex world of Lyme disease, mold toxicity, environmental illness, and whole-body healing. Dr. Kelley had her own health journey with chronic fatigue, POTS, and other symptoms that led her to specialize in Lyme, tick-borne diseases, mold illness, long COVID, and other complex chronic illnesses. She brings clarity, compassion, and years of integrative and functional medicine experience to help patients understand what’s driving persistent symptoms and what true recovery can look like.

“The nervous system is utterly important to healing. And that entire system gets really thrown off with chronic infections exactly the same way that trauma with a capital T will cause dysfunction in the system.”

– Casey Kelley, MD

Better Tests, Better Answers 

Jyotsna Shah, PhD, Ticktective

Bay Area Lyme Leading the Way Series

 

“The IGeneX test is far more sensitive than most commercially available tests for Lyme disease, detecting far more positive patients compared to standard two-tier ELISA or Western Blot tests,”

– Jyotsna Shah, PhD

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For people living with or who suspect Lyme disease, getting a clear diagnosis can feel like the hardest part. Symptoms often mimic those of other illnesses, and traditional tests miss many cases. 

In this episode of Ticktective™, Dr. Jyotsna Shah, President and Laboratory Director of IGeneX, shares with our host, Dana Parish, how her team is changing that—and how Bay Area Lyme Foundation helped make it possible. 

Dr. Shah explains how partnerships between innovative labs like IGenex, Bay Area Lyme Foundation, and our Lyme Disease Biobank are helping deliver faster, more accurate diagnostics—and new hope for patients who’ve struggled for years to find answers.

Dr. Casey Kelley: From Lyme & Mold to Optimum Health

Ticktective Podcasts

Casey Kelley, MD

Dr. Casey Kelley, MD, is a board-certified family medicine physician and one of the first to earn certification in integrative medicine. Founder and medical director of Case Integrative Health in Chicago, she specializes in functional medicine to address root causes of chronic conditions like Lyme disease and mold toxicity. A graduate of Ohio State University College of Medicine (2007), she completed residency at St. Joseph Hospital, lectures nationally on integrative topics, and serves on faculty at Northwestern’s Feinberg School of Medicine.

Dr. Jyotsna Shah: Inside IGeneX’s Game-Changing Lyme Test

Ticktective Podcasts

Jyotsna Shah, PhD

Dr. Jyotsna Shah is an immunologist and molecular biologist with over 40 years of experience in diagnostic tools for tick-borne diseases. She holds a Ph.D. in diagnostic immunology from the University of Nairobi and conducted postdoctoral work at Harvard University. Shah joined IGeneX in 1997, becoming Laboratory Director in 2003 and now serving as President and CEO.

Mikki Tal, PhD: Chronic Infections, Fertility, & Immunity: MIT Immunoengineer Makes Groundbreaking Lyme Discoveries

Ticktective Podcasts

Mikki Tal, PhD

Mikki Tal, PhD, is a Principal Scientist at MIT’s Department of Biological Engineering and Associate Scientific Director of the MIT Center for Gynepathology Research. She leads the Tal Research Group, focusing on host-pathogen interactions, immune responses to infections like Lyme disease, and the mechanisms behind chronic illnesses, particularly their disproportionate impact on women. She earned her PhD in Immunobiology from Yale University and conducted postdoctoral research at Stanford University’s Institute for Stem Cell Biology and Regenerative Medicine. Tal was the recipient of our 2018 Bay Area Lyme Foundation Emerging Leader Award.

Dr. Joe Burrascano: A Masterclass on Tick-Borne Illness

Ticktective Podcasts

Dr. Joe Burrascano

Dr. Joseph J. Burrascano Jr., a pioneer in the field of Lyme, began his practice in East Hampton, NY, in 1981, where he identified and detailed the clinical aspects of Lyme in a high-prevalence area. Renowned for his groundbreaking diagnostic and treatment guidelines since 1984, he has advised the CDC, NIH, and U.S. Senate, authored extensive publications, and is a founding member of ILADS, continuing to educate globally.