Biobank Collection Sites
Submission: Investigators submit an application including a technical proposal, justification for the number of samples requested, funding source, dissemination plan, and CV.
Peer review: Each application is peer-reviewed and scored by an ad-hoc committee of three experts.
Final approval: Applications with competitive scores are presented to the Lyme Disease Biobank board for approval.
Signed paperwork: Blinded and deidentified samples are released upon receipt of an executed MTA, payment, and approval or exemption from the applicant’s IRB.
Liz Horn, PhD, MBI, Principal Investigator
Results to date
Through 3 seasons of collection, ~250 participants have been enrolled at 3 sites (East Hampton, NY, Martha’s Vineyard, MA, Marshfield, WI). Each participant’s donation provides samples for ~50 research projects, with aliquots of whole blood (1 and 2 ml), serum (250 μl), and urine (1 ml). Several larger aliquots (5 ml) are also available. Detailed clinical information is also gathered to better characterize the disease. Currently, samples from the first 2 years of collection (~120) are available to investigators through an application process. Samples collected in 2016 will be available in Spring 2017.
Thank you to all those who participated in this formative stage of the pilot and concept!
Our Lyme disease BioBank is:
- A network of regional collection centers from endemic regions across the country
- A central laboratory that handles all processing and storage
- A consistent set of stringent protocols, validation, and testing
- A BAL supporting organization with strong leadership, and the oversight of a clinical advisory committee to ensure the appropriate rigor and methods
This effort will:
- Substantially increase the amount and diversity of biospecimens available for research
- Include well-annotated clinical data and longitudinal samples
- Enable follow-up and recontact with consenting participants to further clinical assessment and qualification
- Provide standardized and transparent access for qualifying projects
- Create standard vocabulary and lexicon to help build consensus and move the field forward
- Facilitate interaction and collaborations between researchers leading to more research innovation and medical breakthroughs
How Can You Get Involved?
The BioBank is an important undertaking that will dramatically improve research access to quality samples and expedite the discovery of new treatments and diagnostics.
*A June 2013 National Institutes of Standards and Technology (NIST) survey indicated that 84% of the research scientists could not access the samples they need (blood tissue, saliva, etc.) and 96% believed there was a critical need for a centralized biorepository.