Lyme Disease Biobank was initiated with a Fund-A-Need campaign at Bay Area Lyme Foundation’s annual LymeAid® benefit (May, 2014). We have enrolled more than 1,200 participants from eight collection sites on the East Coast, in Upper Midwest, Southern California, and in the Northern California Bay Area. Each participant’s donation provides samples for ~50 research projects, with aliquots of whole blood (1 and 2 ml), serum (250 μl), and urine (1 ml). Several larger aliquots (5 ml) are also available. Detailed clinical information and testing data are also collected to better characterize samples. Currently, more than 80 research projects are using LDB samples. Click here to read a timeline of this program.

You may read the latest published studies using LDB samples and latest news below.

 

Publications


Biobank Published Results

 

Frontiers (2022) –  Testing Raman spectroscopy as a diagnostic approach for Lyme disease patients

 

 

Frontiers (2021) –  Recent Progress in Lyme Disease and Remaining Challenges

 

 

Journal of Clinical Microbiology (2020) – The Lyme Disease Biobank – Characterization of 550 Patient and Control Samples from the East Coast and Upper Midwest of the United States

 

Published Studies Using Lyme Disease Biobank Samples

 

Fronteirs

Frontiers (2022) – Acute lyme disease IgG N-linked glycans contrast the canonical inflammatory signature

 

National Library of Medicine (2022) – Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood

 

National Library of Medicine (2021) – Serum Epitope Repertoire Analysis Enables Early Detection of Lyme Disease with Improved Sensitivity in an Expandable Multiplex Format

 

PLOS One (2020) – A fluorescent plasmonic biochip assay for multiplex screening of diagnostic serum antibody targets in human Lyme disease

 

Computers in Biology and Medicine (2020) – AI-based detection of erythema migrans and disambiguation against other skin lesions

 

National Center for Biotechnology Information (2020) – Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry

 

 

National Center for Biotechnology Information – Pediatric Lyme Disease Biobank, United States, 2015–2020

 

 

ACS Nano (2020) – Point-of-care serodiagnostic test for early-stage Lyme disease using a multiplexed paper-based immunoassay and machine learning

Journal of Clinical Microbiology (2019) – A Multiplexed Serologic Test for Diagnosis of Lyme Disease for Point-of-Care Use

 

 

LDB in the News


2020

NDRI Newsletter (Page 14) – NDRI national survey finds Americans strongly support organ and tissue donation for research

Gordon Medical Lyme Disease Biobank Recruiting in Northern and Southern California 

The East Hampton StarEast Hampton Samples Are a Crucial Contributor to Lyme Test

Outbreak News TodayLyme Disease Biobank Expands Into San Diego

Massachusetts News WireBay Area Lyme Foundation announces Lyme Disease Biobank Expands Into San Diego for 2020

San Diego Union TribuneColumn: Ticking bomb: Lyme disease is not an East Coast phenomenon

Send 2 Press NewswireLyme Disease Biobank Expands Into San Diego

Outbreak News TodayNew Study Shows Less Than One-Third of Lyme Disease Test Results are Accurate for Patients with Lyme Rash

2019

lymedisease.orgDonate samples to Lyme Disease Biobank to aid research

Gordon MedicalLyme Disease Biobank – Recruiting in Northern and Southern California

WFMZ-TV 69Bay Area Lyme Foundation Highlights 2019 Progress toward Diagnosing, Treating and Preventing Lyme Disease

PR NewswireJournal of Clinical Microbiology Publishes First Study Using Samples from the Lyme Disease Biobank

Business InsiderFirst West Coast CME Program on Tick-borne Disease Provides New Data, Insights from Researchers

2018

Outbreak News TodayLyme Disease Biobank expands to increase understanding of disease in heart, brain, joints and other tissues

BiospaceBay Area Lyme Foundation Endorses First Recommendations of New HHS Working Group Focused on Tick Borne Diseases

Markets Insider – Bay Area Lyme Foundation and Project Lyme Join Forces to Fight Lyme Disease at the 2018 Lyme Gala

Advancement of Science (AAAS)Lyme Disease Biobank expands to increase understanding of Lyme in heart, brain, joints

HealthlineHere’s Why Lyme Disease Keeps Spreading in the U.S.

Look to the StarsJay Leno Emcees Bay Area Lyme Foundation’s LymeAid 2018 

PR NewswireBay Area Lyme Foundation’s LymeAid® 2018 Raises $1.1 Million for Lyme Disease Research

 

We would like to recognize and thank the Steven & Alexandra Cohen Foundation, the LaureL STEM Fund, and the 2014 and 2018 Fund-a-Need supporters who have contributed significantly to our Lyme Disease Biobank since 2014.