Lyme Disease Biobank was initiated with a Fund-A-Need campaign at Bay Area Lyme Foundation’s annual LymeAid® benefit (May, 2014). We have enrolled more than 1,200 participants from eight collection sites on the East Coast, in Upper Midwest, and in California. Each participant’s donation provides samples for ~50 research projects, with aliquots of whole blood (1 and 2 ml), serum (250 μl), and urine (1 ml). Several larger aliquots (5 ml) are also available. Detailed clinical information and testing data are also collected to better characterize samples. Currently, more than 80 research projects are using LDB samples. Click here to read a timeline of this program.
You may read the latest published studies using LDB samples and latest news below.
Biobank Published Results
|Cureus (2022 Oct 25) – The spectrum of erythema migrans in early Lyme disease: Can we improve its recognition?|
|Frontiers in Medicine (2021 Aug 18) – Recent progress in Lyme disease and remaining challenges|
|Journal of Clinical Microbiology (2020 May 26) – The Lyme Disease Biobank: Characterization of 550 patient and control samples from the East Coast and Upper Midwest of the United States|
Published Studies Using Lyme Disease Biobank Samples
|Frontiers in Cellular and Infection Microbiology (2022 Oct 27) – Testing Raman spectroscopy as a diagnostic approach for Lyme disease patients|
|Frontiers in Immunology (2022 Aug 5) – Acute lyme disease IgG N-linked glycans contrast the canonical inflammatory signature|
|Frontiers in Microbiology (2022 Mar 7) – Capture sequencing enables sensitive detection of tick-borne agents in human blood|
|Journal of Clinical Microbiology (2021 Jan 21) – Serum epitope repertoire analysis enables early detection of Lyme disease with improved ssensitivity in an expandable multiplex format
|Scientific Reports Nature Research (2020 Dec 10) – Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry
|Plos One (2020 Feb 10) – A fluorescent plasmonic biochip assay for multiplex screening of diagnostic serum antibody targets in human Lyme disease|
Journal of Clinical Microbiology (2019 Nov 22) – A multiplexed serologic test for diagnosis of Lyme disease for point-of-care use
LDB in the News
NDRI Newsletter (Page 14) – NDRI national survey finds Americans strongly support organ and tissue donation for research
Gordon Medical – Lyme Disease Biobank Recruiting in Northern and Southern California
The East Hampton Star – East Hampton Samples Are a Crucial Contributor to Lyme Test
Outbreak News Today – Lyme Disease Biobank Expands Into San Diego
Massachusetts News Wire – Bay Area Lyme Foundation announces Lyme Disease Biobank Expands Into San Diego for 2020
San Diego Union Tribune – Column: Ticking bomb: Lyme disease is not an East Coast phenomenon
Send 2 Press Newswire – Lyme Disease Biobank Expands Into San Diego
lymedisease.org – Donate samples to Lyme Disease Biobank to aid research
Advancement of Science (AAAS) – Lyme Disease Biobank expands to increase understanding of Lyme in heart, brain, joints
Healthline – Here’s Why Lyme Disease Keeps Spreading in the U.S.
Look to the Stars – Jay Leno Emcees Bay Area Lyme Foundation’s LymeAid 2018
We would like to recognize and thank the Steven & Alexandra Cohen Foundation, the LaureL STEM Fund, an anonymous donor, and the 2014 & 2018 LymeAid Fund-a-Need supporters who have contributed significantly to our Lyme Disease Biobank.
We are grateful to the participants who volunteered and donated samples.