Lyme Disease Biobank was initiated with a Fund-A-Need campaign at Bay Area Lyme Foundation’s annual LymeAid® benefit (May, 2014). We have enrolled more than 1,200 participants from eight collection sites on the East Coast, in Upper Midwest, Southern California, and in the Northern California Bay Area. Each participant’s donation provides samples for ~50 research projects, with aliquots of whole blood (1 and 2 ml), serum (250 μl), and urine (1 ml). Several larger aliquots (5 ml) are also available. Detailed clinical information and testing data are also collected to better characterize samples. Currently, more than 80 research projects are using LDB samples. Click here to read a timeline of this program.
You may read the latest published studies using LDB samples and latest news below.
Publications
Biobank Published Results
Frontiers (2022) – Testing Raman spectroscopy as a diagnostic approach for Lyme disease patients
Frontiers (2021) – Recent Progress in Lyme Disease and Remaining Challenges
Journal of Clinical Microbiology (2020) – The Lyme Disease Biobank – Characterization of 550 Patient and Control Samples from the East Coast and Upper Midwest of the United States
Published Studies Using Lyme Disease Biobank Samples
Frontiers (2022) – Acute lyme disease IgG N-linked glycans contrast the canonical inflammatory signature
National Library of Medicine (2022) – Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood
National Library of Medicine (2021) – Serum Epitope Repertoire Analysis Enables Early Detection of Lyme Disease with Improved Sensitivity in an Expandable Multiplex Format
PLOS One (2020) – A fluorescent plasmonic biochip assay for multiplex screening of diagnostic serum antibody targets in human Lyme disease
Computers in Biology and Medicine (2020) – AI-based detection of erythema migrans and disambiguation against other skin lesions
National Center for Biotechnology Information (2020) – Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry
National Center for Biotechnology Information – Pediatric Lyme Disease Biobank, United States, 2015–2020
ACS Nano (2020) – Point-of-care serodiagnostic test for early-stage Lyme disease using a multiplexed paper-based immunoassay and machine learning
Journal of Clinical Microbiology (2019) – A Multiplexed Serologic Test for Diagnosis of Lyme Disease for Point-of-Care Use
LDB in the News
2020
NDRI Newsletter (Page 14) – NDRI national survey finds Americans strongly support organ and tissue donation for research
Gordon Medical – Lyme Disease Biobank Recruiting in Northern and Southern California
The East Hampton Star – East Hampton Samples Are a Crucial Contributor to Lyme Test
Outbreak News Today – Lyme Disease Biobank Expands Into San Diego
Massachusetts News Wire – Bay Area Lyme Foundation announces Lyme Disease Biobank Expands Into San Diego for 2020
San Diego Union Tribune – Column: Ticking bomb: Lyme disease is not an East Coast phenomenon
Send 2 Press Newswire – Lyme Disease Biobank Expands Into San Diego
Outbreak News Today – New Study Shows Less Than One-Third of Lyme Disease Test Results are Accurate for Patients with Lyme Rash
2019
lymedisease.org – Donate samples to Lyme Disease Biobank to aid research
Gordon Medical – Lyme Disease Biobank – Recruiting in Northern and Southern California
WFMZ-TV 69 – Bay Area Lyme Foundation Highlights 2019 Progress toward Diagnosing, Treating and Preventing Lyme Disease
PR Newswire – Journal of Clinical Microbiology Publishes First Study Using Samples from the Lyme Disease Biobank
Business Insider – First West Coast CME Program on Tick-borne Disease Provides New Data, Insights from Researchers
2018
Outbreak News Today – Lyme Disease Biobank expands to increase understanding of disease in heart, brain, joints and other tissues
Markets Insider – Bay Area Lyme Foundation and Project Lyme Join Forces to Fight Lyme Disease at the 2018 Lyme Gala
Advancement of Science (AAAS) – Lyme Disease Biobank expands to increase understanding of Lyme in heart, brain, joints
Healthline – Here’s Why Lyme Disease Keeps Spreading in the U.S.
Look to the Stars – Jay Leno Emcees Bay Area Lyme Foundation’s LymeAid 2018
PR Newswire – Bay Area Lyme Foundation’s LymeAid® 2018 Raises $1.1 Million for Lyme Disease Research
We would like to recognize and thank the Steven & Alexandra Cohen Foundation, the LaureL STEM Fund, and the 2014 and 2018 Fund-a-Need supporters who have contributed significantly to our Lyme Disease Biobank since 2014.