The Lyme Disease Biobank was initiated with a Fund-A-Need campaign at Bay Area Lyme Foundation’s annual LymeAid® benefit (May 2014), we have enrolled more than 1,000 participants from eight collection sites on the East Coast, in Upper Midwest, Southern California, and in the Northern California Bay Area. Each participant’s donation provides samples for ~50 research projects, with aliquots of whole blood (1 and 2 ml), serum (250 μl), and urine (1 ml). Several larger aliquots (5 ml) are also available. Detailed clinical information and testing data are also collected to better characterize samples. Currently, more than 70 research projects are using biobank samples.
You may read the latest published studies using LDB samples and latest news below.
Biobank Published Results
Frontiers (2021) – Recent Progress in Lyme Disease and Remaining Challenges
Journal of Clinical Microbiology (2020) – The Lyme Disease Biobank – Characterization of 550 Patient and Control Samples from the East Coast and Upper Midwest of the United States
Published Studies Using Lyme Disease Biobank Samples
National Library of Medicine (2022) – Capture Sequencing Enables Sensitive Detection of Tick-Borne Agents in Human Blood
National Library of Medicine (2021) – Serum Epitope Repertoire Analysis Enables Early Detection of Lyme Disease with Improved Sensitivity in an Expandable Multiplex Format
Computers in Biology and Medicine (2020) – AI-based detection of erythema migrans and disambiguation against other skin lesions
National Center for Biotechnology Information (2020) – Rapid and sensitive detection of SARS-CoV-2 antibodies by biolayer interferometry
National Center for Biotechnology Information – Pediatric Lyme Disease Biobank, United States, 2015–2020
Journal of Clinical Microbiology (2019) – A Multiplexed Serologic Test for Diagnosis of Lyme Disease for Point-of-Care Use
LDB in the News
NDRI Newsletter (Page 14) – NDRI national survey finds Americans strongly support organ and tissue donation for research
Gordon Medical – Lyme Disease Biobank Recruiting in Northern and Southern California
The East Hampton Star – East Hampton Samples Are a Crucial Contributor to Lyme Test
Outbreak News Today – Lyme Disease Biobank Expands Into San Diego
Massachusetts News Wire – Bay Area Lyme Foundation announces Lyme Disease Biobank Expands Into San Diego for 2020
San Diego Union Tribune – Column: Ticking bomb: Lyme disease is not an East Coast phenomenon
Send 2 Press Newswire – Lyme Disease Biobank Expands Into San Diego
lymedisease.org – Donate samples to Lyme Disease Biobank to aid research
Advancement of Science (AAAS) – Lyme Disease Biobank expands to increase understanding of Lyme in heart, brain, joints
Healthline – Here’s Why Lyme Disease Keeps Spreading in the U.S.
Look to the Stars – Jay Leno Emcees Bay Area Lyme Foundation’s LymeAid 2018
We would like to recognize and thank the Steven & Alexandra Cohen Foundation, the LaureL STEM Fund, and the 2014 and 2018 Fund-a-Need supporters who have contributed significantly to our Lyme Disease Biobank since 2014.